Organic Acids
Medchemexpress LLC Dendrotoxin K TFA | 119128-61-9 | 6559.66 | 500 UG
Dendrotoxin K functions as a Kv1.1 channel blocker. It plays a role in determining glutamate release within CA3 neurons by controlling the presynaptic spike waveform in a time-dependent manner.
- Acts as a Kv1.1 channel blocker.
- Influences glutamate release in CA3 neurons.
- Regulates the presynaptic spike waveform in a time-dependent manner.
- Intended for research use only.
Medchemexpress LLC PHF6 TFA | 99.5% | 748.91 | 5 MG
PHF6 (VQIVYK) TFA is a self-assembly sequence capable of initiating the full-length tau protein aggregation. PHF6 TFA is mapped to the third microtubule-binding repeat region of the tau protein.
- Aggregated tau-PHF6 (VQIVYK) TFA potentiates NLRP3 inflammasome expression and autophagy in human microglial cells.
Medchemexpress LLC Pyridostatin (TFA) | 1472611-44-1 | 1037658 | C33H33F3N8O7 | 25 MG
Pyridostatin TFA is a G-quadruplex DNA stabilizing agent with a Kd of 490 nM, targeting both DNA and RNA G4s within cells. This selective small molecule promotes growth arrest in human cancer cells by inducing replication- and transcription-dependent DNA damage and affects proto-oncogene Src.
- Targets DNA and RNA G4s in cells
- Promotes growth arrest in human cancer cells
- Induces replication- and transcription-dependent DNA damage
- Reduces SRC protein levels and cellular motility in breast cancer cells
- Causes neurite retraction, synaptic loss, and dose-dependent neuronal death in cultured primary neurons
- Induces DNA DSBs in cultured primary neurons
- Downregulates BRCA1 protein at the transcriptional level
- High purity: 99.17%
- Solid, white to off-white appearance
Medchemexpress LLC Cyclo(RGDyC) TFA | 95.68% | 594.64 | 1 MG
Cyclo(RGDyC) TFA is a cyclic pentapeptide with anti-angiogenic abilities. It can be combined with liposome delivery systems for research on ocular neovascular diseases and cancer.
- Cyclic pentapeptide
- Anti-angiogenic abilities
- Contains the alphaVbeta3 integrin-binding sequence arginine-glycine-aspartate (RGD)
- Can be used to target tumors and ocular neovasculature
- White to off-white solid appearance
- Soluble in H2O
Medchemexpress LLC HR97 TFA | 1518.84 | 5 MG
HR97 TFA is a cell-penetrating peptide that can be combined with engineered melanin to prepare eye drops HR97-SunitiGel. The peptide-drug conjugate in HR97-SunitiGel can provide sustained ocular drug delivery.
- Cell-penetrating peptide
- Molecular weight of 1518.84 (free acid)
- Sequence: Phe-Ser-Gly-Lys-Arg-Arg-Lys-Arg-Lys-Pro-Arg-Cys
- Solubility in DMSO: 50 mg/mL (requires ultrasonic)
- Can be used to prepare HR97-SunitiGel eye drops
Medchemexpress LLC Cppi9 Tfa | 99.9% | 1553.37 | 5 MG
CPP9 TFA is a small, amphipathic, cyclic cell-penetrating peptide (CPP) that binds directly to plasma membrane phospholipids and enters mammalian cells via endocytosis. Its efficient release from the endosome after cellular entry makes it suitable for intracellular delivery of therapeutic agents and chemical probes.
- Efficient release from endosome after cellular entry
- Suitable for intracellular delivery of therapeutic agents
- Suitable for intracellular delivery of chemical probes
- For research use only
Medchemexpress LLC Charybdotoxin (TFA) | 96.8% | 4295.89 (free acid) | 500 UG
Charybdotoxin (TFA) is a research-grade peptide supplied as a white to off-white solid. It has a molecular weight of 4295.89 (free acid) and a purity of 96.8% as determined by LCMS. This substance is intended for laboratory use and substance manufacturing, offering stability under recommended storage conditions.
- Supplied as a white to off-white solid
- Purity of 96.8% (LCMS)
- Molecular weight of 4295.89 (free acid)
- Suitable for use as laboratory chemical and for substance manufacturing
- Stable under recommended storage conditions
- Store powder at -80°C for 2 years or -20°C for 1 year
- Store in solvent at -80°C for 6 months or -20°C for 1 month
Medchemexpress LLC Ghrf, mouse (TFA) | 125199-49-7 | 98.9% | 5032.74 | 5 MG
GHRF, mouse (TFA) is a 44-amino acid peptide that stimulates the release and synthesis of growth hormone. This product is for research use only and not intended for patient use.
- 44-amino acid peptide
- Stimulates growth hormone release and synthesis
- High purity of 98.9%
- Molecular weight of 5032.74
- Increases growth hormone levels in LI-IGF-I-/- mice
eMolecules 407-22-7 | 2-Fluoro-6-methylpyridine | Ambeed | MFCD00041226 | 111.119 | C6H6FN | 97.000 | Cc1cccc(F)n1 | 5g | 552650211
2-Fluoro-6-methylpyridine | Ambeed | 407-22-7 | MFCD00041226 | 111.119 | C6H6FN | 97.000 | Cc1cccc(F)n1 | 5g | 552650211
